| Format & access | Compounded prescription cream | Retail acne moisturizer | Compounded prescription cream | Retail acne moisturizer | Retail leave-on acne gel | Retail acne moisturizer | Retail leave-on acne gel | Targeted retail acne gel | Targeted retail cream |
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| Acne active | Salicylic acid 2% in the current linked offer. | Salicylic acid 0.5% in the brand declaration and submitted label. | Salicylic acid, zinc oxide, niacinamide and urea; strengths are not listed in the headline | Salicylic acid 0.5% in the product description and submitted label. | Salicylic acid 2% listed as the acne active. | Salicylic acid 0.5% in the manufacturer information and submitted acne label. | Salicylic acid 1% in the original gel’s OTC label. Separate Advanced product is 2%. | Salicylic acid 2% in the manufacturer declaration. | Salicylic acid 1%, distinct from the 2% succinic acid headline. |
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| The rest of the formula | Also publishes zinc oxide 5%, niacinamide 8% and urea 2%. Confirm the complete prescribed base. | Includes moisturizing ingredients such as glycerin, dimethicone and squalane. Check the current package. | Salicylic acid, zinc oxide, niacinamide and urea; strengths are not listed in the headline | Includes hyaluronic acid forms and niacinamide. DailyMed describes the dosage form as gel. | Also includes glycolic and lactic acids, niacinamide and ceramides. AHA sunburn alert applies. | Soybean extract, glycerin and silicones in the submitted declaration, which also lists fragrance. Hypoallergenic does not mean fragrance-free. | Includes alcohol denat., witch hazel water and alcohol. Fragrance-free positioning does not mean alcohol-free. | Includes alcohol and witch hazel water. Check the current package; this is not a moisturizing cream. | Also 2% sulfur and 0.4% hyaluronic acid. Full panel includes colloidal sulfur, glycerin and squalane. |
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| Purchase snapshot | 12 months $504, displayed $42/month; one month $70, displayed $69.99. Confirm actual supply and terms. | Direct price not established. Older label lists 3 fl oz / 89 mL; confirm the selected retailer package. | $42/month | $12.99 for 80 mL shown on the US page. Single product, not the complete acne system. | $20.99 displayed on the US page. Selected size-to-price pairing not established; confirm with seller. | Direct price not established. Submitted April 2025 label identifies 4 fl oz / 118 mL; confirm the selected package. | US 1 fl oz $34 or 0.5 fl oz $23. Single-container snapshots; no checkout or delivery test. | $29 / 0.5 fl oz public offer on September 27; available variant, no completed checkout. | US $15 / 15 mL public variant available September 27; checkout not tested. |
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| Evidence limits | Provider claims; no finished-formula controlled trial established here. Compounded drugs are not FDA-approved. | Manufacturer hydration and consumer-response claims. Older label and current website differ in an ingredient detail. | These are provider-published terms checked October 4, 2026. Prescription approval is conditional. Compounded medications are not FDA-approved; we have not tested the treatment, pharmacy fulfillment or patient outcomes. | Ingredient and supplier research, consumer feedback and collection-wide images are different evidence categories. | Manufacturer benefit claims. A broader brand recommendation survey does not prove this gel outperforms alternatives. | Tone and texture positioning is manufacturer information. No independently appraised superiority trial of this current formula established here. | Overnight claim is consumer feedback after two uses. Short clinical comparison summary does not establish independent equivalence to a prescription. | Rapid appearance claims are manufacturer statements. Full clinical methods not independently appraised; testimonials and AI summaries excluded. | Fast improvement and non-drying are manufacturer claims. No complete comparative clinical report established; prescription compatibility needs clinician input. |
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| Full review | Read CoreAge Rx → | Read Cetaphil → | Read Likeness Rx → | Read Peach Slices → | Read CeraVe → | Read Aveeno → | Read Clinique → | Read Murad → | Read The INKEY List → |
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